Even a single meal of pizzas and burgers could put you at risk of diabetes, liver diseases

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A new study has claimed that even a single meal of high-fat meal comprising of pizzas and burgers could put you at risk of diabetes and liver diseases.

According to a study published in the Journal of Clinical Investigation by scientists from German Diabetes Center and the Helmholtz Center in Munich, even a one-off consumption of a greater amount of palm oil reduces the body’s sensitivity to insulin and causes increased fat deposits as well as changes in the energy metabolism of the liver.

Researchers found evidence on the earliest changes in the metabolism of the liver that in the long term lead to fatty liver disease in overweight persons as well as in those with Type-2 diabetes. Scientists say they are surprised that even a single dosage of palm oil has such a rapid and direct impact on the liver of a healthy person.

For the study they asked healthy, slim men, at random, to drink a flavored palm oil drink or a glass of clear water in a control experiment. The palm oil drink contained a similar amount of saturated fat as two cheeseburgers with bacon and a large portion of French fries or two salami pizzas.

It showed that this single high-fat meal sufficed to reduce the insulin action, e.g. cause insulin resistance and increase the fat content of the liver. In addition, changes in the energy balance of the liver were proven. The observed metabolic changes were similar to changes observed in persons with type 2 diabetes or non-alcoholic fatty liver disease (NAFLD).

The scientists were able to verify that the intake of palm oil affects the metabolic activity of muscles, liver and fatty tissue.

The increased availability of fat leads to an increased workload for the mitochondria, which can in the long term overtax these cellular power plants and contribute to the emergence of a liver disease.

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